Healthy

Washington – The discovery of particles that the immune system to attack the AIDS virus, eventually opening a way to make vaccines that can protect people from deadly disease transmission and can not be cured it, U.S. researchers said Thursday (3 / 9) then.

They use new technology for fishing through the blood of the 1,800 people who have been infected with the AIDS virus and the immune system to identify two compounds called antibodies neutralizing the virus.

They found a new part of the virus antibody attackers, who opened the way of making vaccines, they report in the journal Science.

“Hence, now we get a better chance to design a vaccine that would produce such a broader neutralizing antibody, and we think it is key to success in vaccine development,” said Dennis Burton of Scripps Research Institute in La Jolla, California, who led the research these.

“The discovery itself is an encouraging progress in AIDS vaccine is effective because we now have a new target with a potentially better understanding of HIV, which focuses our efforts in making vaccines,” adds Wayne Koff of the International AIDS Vaccine Initiative (IAVI), sponsor of the study.

AIDS epidemic since the early 1980s, more than 25 million people globally died from the virus. World Health Organization estimates there are now 33 million people have been infected.

Can not be cured, although there are medicines that can help suppress the virus control. Vaccine manufacturing efforts almost always fail. Viruses can change

Part of the mutations cause so much for everyone who is infected with millions of different versions, each showing a different immune system.

In addition, the virus infects the immune cells that is expected to help protect the body. And if there is a virus past the immune defenses, it seems only will develop a persistent infection. There are no drugs capable of combating it.

Director of IAVI, Dr. Seth Berkley, said the findings will form the vaccine was not directly, but indicates there is something new and better ways to manufacture.

He said 10 percent of patients whose blood was checked for having a strong antibody response to the virus. “We have people with the serum even stronger out there. Possibly we will find more,” he said in a telephone interview.

This possibility can also be used as therapeutic antibodies themselves-such as gamma globulin used in viral hepatitis. But the final destination, Berkley said, an antibody-producing vaccine can stop the virus that had infected the person in the first place.

“We have not been able to do that because we’ve never been able to find a response that really right,” said Berkley.

Most vaccines generate antibody responses, with a thorough body to make antibodies that will recognize and attack the germs such as viruses or bacteria.

Two antibodies, PG9 and PG16, is the first new HIV antibodies that have been identified more than 10 years. They are targeting a part to stop the virus infects cells, the researchers wrote.

A team in South San Francisco, Monogram Biosceiences Inc. has examined blood to find neutralizing HIV. Theaclone Sciences uses this technology to identify antibody required.

Laboratory Corp. of America Holdings is headquartered in North Carolina have found the monogram this past July. (Voice)